

HY-124954 · 1 mg
MedChemExpress · Cat: HY-124954
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medchemexpress.com/mn-25.htmlDescription
MN-25 compound 4a is an orally active indolpyridone that serves as a novel cannabinoid ligand. MN-25 has Ki of 245 nM and 11 nM for CB1 and CB2. MN-25 has CB2 agonist activity and inhibits TNF-R release in human peripheral blood mononuclear cells in vitro with an IC50 of 33 ?M. MN-25 shows efficacy in a mouse acute inflammation model at oral doses up to 50 mg/kg> 1 .







