MLK4 Rabbit Polyclonal Antibody

Description

EnkiLife offers the MLK4 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,IHC,ELISA application. Alternative Names of Immunogen: MLK4; KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000 Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein. cofactor:Magnesium. enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation. function:Activates the JUN N-terminal pathway. PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. similarity:Contains 1 protein kinase domain. similarity:Contains 1 SH3 domain. subunit:Homodimer.