GENERAL CATALOGUE
ML115
HY-111152 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-111152
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Catalog No: HY-111152
CAS No: 912798-42-6
Category: JAK STAT Signaling
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC50 of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-?B anti-targets. ML115 counteracts the effects of Ginsenoside Rc HY-N0042 on cell viability and inflammatory responses in LPS HY-D1056 -stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers.
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