GENERAL CATALOGUE
MI-1061 TFA
HY-125858A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-125858A
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Catalog No: HY-125858A
CAS No: 1410737-35-7
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
MI-1061 TFA is a potent, orally bioavailable, and chemically stable MDM2 MDM2-p53 interaction inhibitor IC50=4.4 nM; Ki=0.16 nM . MI-1061 TFA potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity.