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LY2874455, FGF/FGFR inhibitor
ab216313 · 5 mg
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Catalog No: ab216313
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 444.3 Da, Purity >98 %. Potent FGF/FGFR inhibitor. Inhibits in vitro autophosphorylation of FGFR-1, FGFR-2, FGFR-3, and FGFR-4 with similar inhibition potency for all four FGFRs IC50 < 6.4 nM . Exhibits a 6- to 9-fold in vitro and in vivo selectivity on inhibition of FGF- over VEGF-mediated target signaling in mice.
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