

HY-19916 · 5 mg
MedChemExpress · Cat: HY-19916
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Manufacturer product page
medchemexpress.com/lisavanbulin.html
Description
Lisavanbulin BAL-101553 is the prodrug of the microtubule targeting agent Avanbulin BAL 27862 HY-106008 . Lisavanbulin is a BBB-penetrant and orally active antitumor agent, especially in tumors that express high levels of end-binding protein 1. Lisavanbulin has ability to target tumor cell proliferation and affects the tumor microenvironment by reducing tumor microvasculature. Lisavanbulin is also a spindle assembly checkpoint activator. Lisavanbulin induces cell cycle arrest and subsequent death or aberrant chromosome segregation. Lisavanbulin can be studied in research for diffuse large B cell lymphoma DLBCL and glioblastoma.





