Brand Store/abcam/Leptomycin B (ethanol solution), Antibiotic, antifungal. Inhibitor of CRM-1 mediated nuclear export.
BRAND STORE
Leptomycin B (ethanol solution), Antibiotic, antifungal. Inhibitor of CRM-1 mediated nuclear export.
ab120501 · 5 µg
AB
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Catalog No: ab120501
Category: Biochemicals
Pack Size: 5 µg
Brand: abcam
Description
MW 540.7 Da, Purity >95 %. Potent inhibitor of CRM-1-mediated exportin-1 nuclear export. Displays antibiotic, antifungal, and antitumor properties and blocks the cell cycle at G1 and G2 phases. Potent inhibitor of nucleo-cytoplasmic translocation of Rev. Also shown to suppress HIV-1 replication in human monocytes IC50 = 600 pM .
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