LC3-I (human), (recombinant) (His-tag)

Description

The generic term autophagy comprises several processes by which the lysosome acquires cytosolic cargo, with three types of autophagy being discerned in the literature: 1 macroautophagy, characterized by the formation of a crescent-shaped structure the phagophore that expands to form the double-membrane autophagosome, capable of fusion with the lysosome; 2 microautophagy, in which lysosomes invaginate and directly sequester cytosolic components; and 3 chaperone-mediated autophagy CMA , which involves translocation of unfolded proteins across the lysosomal membrane