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KN-62, CaM kinase II inhibitor. P2X7 antagonist.
ab120421 · 1 mg
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Catalog No: ab120421
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 721.8 Da, Purity >98 %. Cell-permeable, reversible and selective inhibitor of CaM kinase II IC50 = 500 nM . Interacts with the calmodulin binding site of the enzyme. At higher concentrations reported to inhibit GSK3beta, PRAK and MAPKAP-K2. Also potent non-competitive antagonist at the P2X7 receptor IC50 = 15 nM .
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