KD-Validated FLI1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated FLI1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:FLI1; Fli-1 Proto-Oncogene, ETS Transcription Factor; SIC-; EWSR2; FLI-1; Friend Leukemia Integration 1 Transcription Factor; Friend Leukemia Virus Integration 1; Transcription Factor ERGB; Ewing Sarcoma Breakpoint Region 2; Proto-Oncogene Fli-1; BDPLT21 Background: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] Research Area: Cell Biology,Epigenetics and Nuclear Signaling,Metabolism,Cancer