ioOligodendrocyte-like cellsTM - Human iPSC derived cells

Description

ioOligodendrocyte-like cells are highly characterised cells that resemble a pre-myelinating oligodendrocyte state. These cells enable the screening of compounds that modulate myelination, supporting drug development for neurodegenerative and demyelinating diseases, such as multiple sclerosis. ioOligodendrocyte-like cells are precision reprogrammed from human iPSC using opti-ox technology, meaning scalability and consistency are built-in. Upon thawing day 1 , cells are ready for experimentation and express the oligodendroglial lineage marker O4. By simply maintaining cells in a monolayer culture, cells rapidly mature and acquire a typical oligodendrocyte-like morphology with multiple branched processes. Cells start expressing oligodendrocyte markers, including MBP, PLP1, CNP and MAG.