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IMD 0354, IKKbeta inhibitor
ab144823 · 5 mg
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Catalog No: ab144823
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 383.67 Da, Purity >98 %. Potent, selective cell-permeable IKKbeta inhibitor IC50 = 250 nM . Blocks IkappaBalpha phosphorylation and prevents NF-kappaB p65 nuclear translocation. Reduces IL-1beta and MCP-1 production. Shows antiproliferative effects. Shows anti-inflammatory effects in vivo. .
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