

ab142070 · 20 mg
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Description
MW 589.7 Da, Purity >98 %. Potent, selective inhibitor of tyrosine kinases v-Abl IC50 = 38 nM , PDGFR and c-kit. Potent inhibitor of the Bcr-Abl tyrosine kinase created by the Philadelphia chromosome abnormality found in CML. Decreases proliferation and enhances apoptosis in leukemias CML and ALL.






