
ab287060 · 1 mg
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Description
MW 555.4 Da, Purity >98 %. Potent and highly specific MDM-2/p53 inhibitor. It binds to human MDM2 protein with a picomolar Ki value 0.21 nM . It activates p53 and induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells.