GENERAL CATALOGUE
HDAC3-IN-4
HY-159172 · 50 mg
MedChemExpress · Cat: HY-159172
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medchemexpress.com/hdac3-in-4.htmlCatalog No: HY-159172
CAS No: 2988762-46-3
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDAC3-IN-4 is a selective and orally active HDAC3 inhibitor with an IC50 of 89 nM. HDAC3-IN-4 induces the degradation of PD-L1 by regulating cathepsin B CTSB in the lysosomes, with a DC50 of 5.7 ?M. HDAC3-IN-4 shows better selectivity for HDAC3 over HDAC1, HDAC6, HDAC7, and HDAC8.