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GSK343, histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor
ab218610 · 1 mg
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Catalog No: ab218610
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 541.7 Da, Purity >99 %. Potent, selective, cell-permeable histone H3-lysine 27 H3K27 methyltransferase EZH2 inhibitor. Inhibits EZH2 enzymatic activity IC50 = 4 nM . Displays 60 fold selectivity for EZH2 over EZH1, and 1000 fold or greater selectivity against other histone methyltransferases. Inhibits H3K27 methylation in HCC1806 cells IC50 < 200 nM .
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