GENERAL CATALOGUE
GNE-987 GSH linker-2
HY-138634 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-138634
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Manufacturer product page
medchemexpress.com/protac-brd4-degrader-11.htmlCatalog No: HY-138634
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GNE-987 GSH linker-2 compound 9a is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. GNE-987 GSH linker-2 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively.