GENERAL CATALOGUE
Gliquidone
HY-B1114 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B1114
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Catalog No: HY-B1114
CAS No: 33342-05-1
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Gliquidone can bind to the pancreatic ?-cells and increases insulin release to regulate blood glucose levels. Gliquidone significantly decreases LPS HY-D1056 -induced proinflammatory responses and inhibits ERK/STAT3/NF-?B phosphorylation in BV2 microglial cells. Gliquidone can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone also exhibits good anticancer activity in lung carcinoma cells. Gliquidone has antioxidant property. Gliquidone can be studied in research for type 2 diabetes and cancers.
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