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Gliotoxin, NF-kappaB inhibitor
ab142437 · 5 mg
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Catalog No: ab142437
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 326.4 Da, Purity >98 %. Specfic NF-kappaB inhibitor. Induces apoptosis and suppresses TNF-alpha gene expression in vitro. Farnesyltransferase and geranylgeranyltransferase I inhibitor IC50 = 80 and 17 muM respectively . Mycotoxin antibiotic. Immunosuppressive, anti-inflammatory and antitumor agent. Active in vivo and in vitro. Orally active.
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