GENERAL CATALOGUE
Fibrostat
HY-169940 · 50 mg
MedChemExpress · Cat: HY-169940
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medchemexpress.com/fibrostat.html
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Catalog No: HY-169940
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
Fibrostat Compound 5n is a selective HDAC6 inhibitor that exerts antifibrotic effects by inhibiting HDAC6 activity, with an IC50 value of 63 nM. It also exhibits good selectivity over HDAC1, HDAC3, HDAC5, HDAC8, HDAC10, and HDAC11. Fibrostat significantly downregulates fibrotic markers fibronectin and collagen 1 in fibroblasts. Additionally, Fibrostat demonstrated no toxicity in rat-perfused heart and zebrafish larvae models. Fibrostat shows potential for research into fibrosis-related diseases.
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