GENERAL CATALOGUE
FGT-4
HY-172934 · 50 mg
MedChemExpress · Cat: HY-172934
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Manufacturer product page
medchemexpress.com/fgt-4.htmlCatalog No: HY-172934
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
FGT-4 is a folate receptor ? FR-? targeting chimeric molecule. FGT-4 is a TLR7 agonist. FGT-4 facilitates the secretion of iNOS and proinflammatory cytokine IL-6 associated with M1 macrophages and enhances the proliferation of cytotoxic CD8+ T cells. FGT-4 has anti-tumor activity in the 4T1 breast cancer mouse model. FGT-4 can be used for the study of cancer immunity. Pink: target protein TLR7/8 agonist 1 ligand HY-103698 ; black: linker HY-172936 ; blue: FR-? ligand HY-172935 .
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