GENERAL CATALOGUE
Fazirsiran sodium
HY-132604A · 1 mg
MedChemExpress · Cat: HY-132604A
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medchemexpress.com/fazirsiran-sodium.htmlCatalog No: HY-132604A
CAS No: 2175009-09-1
Category: Epigenetics
Pack Size: 1 mg
Brand: MedChemExpress
Description
Fazirsiran sodium is a second-generation RNAi agent. Fazirsiran sodium consistes of a cholesterol-conjugated RNAi trigger chol-RNAi to selectively degrade Alpha1-antitrypsin AAT mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine NAG formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes. Fazirsiran sodium can be used in the study of Alpha-1 Antitrypsin Deficiency AATD liver disease.