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Ezetimibe, cholesterol absorption inhibitor
ab254455 · 20 mg
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Catalog No: ab254455
Category: Biochemicals
Pack Size: 20 mg
Brand: abcam
Description
MW 409.4 Da, Purity >98 %. Potent selective cholesterol absorption inhibitor. Inhibits cholesterol absorption in the intestine by preventing uptake by the Niemann-Pick C1-like 1 NPC1L1 protein, a cholesterol transporter. Ezetimibe reduces plasma cholesterol levels from 964 to 374 mg/dL, from 726 to 231 mg/dL, and from 516 to 178 mg/dL in the western, low-fat, and cholesterol-free diet mice, respectively.
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