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GENERAL CATALOGUE
EXQ-2d
HY-168925 · 50 mg
MedChemExpress · Cat: HY-168925
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Manufacturer product page
medchemexpress.com/exq-2d.htmlCatalog No: HY-168925
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
EXQ-2d is the inhibitor for tankyrase and inhibits TNKS1 and TNKS2 with an IC50 of 48.8 nM and 13.8 nM pIC50=7.31 and 7.86 . EXQ-2d inhibits WNT/?-catenin signaling pathway with IC50 of 515 nM. EXQ-2d exhibits anti-proliferative activity in cancer cells COLO 320DM and RKO with GI50 of 4.9 ?M and 77 ?M.