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EX-527, SIRT1 Inhibitor
ab141506 · 1 mg
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Catalog No: ab141506
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 248.71 Da, Purity >97 %. Selective, cell-permeable SIRT1 Inhibitor. IC50= 98 nM, 19.6, 48.7 and 100 muM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively. Shows no effect at other HDACs or SIRTs. Enhances p53 acetylation in response to DNA damaging agents.
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