
ab285394 · 1 mg
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Description
MW 315.32 g/mol, Purity >95 %. A small molecule hydroxamic acid derivative that acts as a HDAC11-selective inhibitor. Reporter assays using a luciferase-linked Foxp3 promoter shows that HDAC11 decreases the signal driven by NFkappaB/p65, alone or in the presence of transfected Foxp3, and impairs luciferase activity driven by p65, Foxp3 and the HAT enzyme, p300.






