

HY-168336 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-168336
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medchemexpress.com/e0924g.htmlDescription
E0924G is an orally active activator for PPAR? with EC50 of 2.82 ?M. E0924G promotes the upregulation of osteoprotegerin OPG with an EC50 of 0.29 ?M. E0924G reduces RANKL-induced osteoclast differentiation and inhibites F-actin ring formation in RAW264.7 macrophages. E0924G regulates the bone density and bone loss in ovariectomized OVX and age-related osteoporosis models.





