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E-4031 dihydrochloride, HERG K+ channel blocker
ab120158 · 5 mg
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Catalog No: ab120158
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 474.4 Da, Purity >99 %. Type III antiarrhythmic drug that blocks ion channels encoded by the ether-a-go-go related gene ERG1 or KCNH1 . Blocks channels in the open configuration with little effect on the channels in the closed configuration. The IC50 for block of human ERG channels in expression systems is approx. 350 nM.
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