

ab120463 · 5 mg
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Description
MW 408.6 Da, Purity >99 %. Potent, cell-permeable dynamin I and dynamin II inhibitor IC50 values are 1.3 and 14.2 muM for inhibition of dynamin I and II GTPase, respectively . Targets the GTPase domain at an allosteric site. Potently inhibits receptor-mediated and synaptic vesicle endocytosis IC50 values are 5 and 41.1 muM, respectively . 15-fold more active than Dynasore ab120192 against dynamin I.






