GENERAL CATALOGUE
Dynole 2?24
HY-145080 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-145080
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Catalog No: HY-145080
CAS No: 1416313-72-8
Category: Cytoskeleton
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Dynole 2?24 is an indole-based dynamin GTPase inhibitor IC50=0.56 ?M for dynamin I . Dynole 2?24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells IC?? CME =1.9 ?M . Dynole 2?24 also shows 4.4-fold selectivity for dynamin I. Dynole 2?24 is active in-cell inhibitor of clathrin-mediated endocytosis. CME: Clathrin mediated endocytosis