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Daminozide, histone demethylase KDM2/7 subfamily inhibitor
ab144621 · 50 mg
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Catalog No: ab144621
Category: Biochemicals
Pack Size: 50 mg
Brand: abcam
Description
MW 160.17 Da, Purity >98 %. Selective histone demethylase KDM2/7 subfamily inhibitor IC50 values are 0.55, 1.5 and 2.1 muM for PHF8, KDM2A and KDM7A respectively . Exhibits 60-fold selectivity for KDM2/7 demethylases over other histone demethylases KDM3, KDM4, KDM5, KDM6 and 2-oxoglurate oxygenases FIH, PHD2, BBOX1 IC50 values 100 muM. Active in vitro. Cell-permeable.
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