GENERAL CATALOGUE
CX-5461 dihydrochloride
HY-13323A · 5 mg
MedChemExpress · Cat: HY-13323A
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Manufacturer product page
medchemexpress.com/CX-5416_HCl.htmlCatalog No: HY-13323A
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II IC50 ?25 ?M .