GENERAL CATALOGUE
CS-VIP 8 hydrochloride
HY-P10948A · 500 g
MedChemExpress · Cat: HY-P10948A
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medchemexpress.com/cs-vip-8-tfa.htmlCatalog No: HY-P10948A
Category: Epigenetics
Pack Size: 500 g
Brand: MedChemExpress
Description
CS-VIP 8 hydrochloride is a selective allosteric WDR5 protein inhibitor Ki= 0.008 ?M . CS-VIP 8 hydrochloride induces conformational changes in the MLL1 complex, leading to the dissociation of MLL1 from the complex, inhibiting MLL1 histone methyltransferase activity and regulating HOX gene expression. CS-VIP 8 hydrochloride is promising for research of hematological diseases such as leukemia.