

HY-116090 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-116090
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medchemexpress.com/conoidin-a.htmlDescription
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II TgPrxII with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 ?M. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII but not PrxIII . Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease.







