

HY-W748582 · 1 mg
MedChemExpress · Cat: HY-W748582
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medchemexpress.com/clozapine-n-oxide-d8.htmlDescription
Clozapine N-oxide-d8 is the deuterium labeled Clozapine N-oxide HY-17366 . Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors DREADDs agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide cant cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor EC50=11 nM agonist.







