
ab254224 · 25 mg
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Description
MW 393.9 Da, Purity >99 %. Ca2+-sensing receptor agonist that is clinically used to treat secondary hyperparathyroidism with chronic kidney disease. Cinacalcet also displays anti-fibrotic activity. Decreases levels of parathyroid hormone PTH , increases adiponectin secretion, lowers oxidative stress and displays anti fibrotic activity. Increases sensitivity of Ca2+-sensing receptors to serum Ca2+ levels. In vivo. Decreases renal epithelial-to-mesenchymal transition EMT and prevents the development of renal fibrosis.






