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CI-994, HDAC inhibitor. Cell-permeable.
ab142098 · 50 mg
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Catalog No: ab142098
Category: Biochemicals
Pack Size: 50 mg
Brand: abcam
Description
MW 269.3 Da, Purity >99 %. Potent, selective HDAC inhibitor Ki values are 0.41 HDAC1 , 0.75 HDAC3 , 100 HDAC6 , and 100 HDAC8 muM respectively . Induces histone H3 hyperacetylation, cell differentiation and apoptosis. Inhibits proliferation and modulates G1 cell cycle arrest. Antitumor agent. Active in vivo and in vitro. Orally active. Blood-brain barrier and cell-permeable.
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