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Chelerythrine chloride, Cell-permeable protein kinase C inhibitor
ab120600 · 5 mg
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Catalog No: ab120600
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 383.8 Da, Purity >98 %. Cell-permeable, selective inhibitor of protein kinase C IC50 = 0.66 muM ; Competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Activates MAPK pathways, independent of PKC inhibition. Inhibits BclXL function IC50 = 1.5 muM by displacing Bax binding, inducing apoptosis in several cancer cell lines.
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