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CeefourinTM 1, MRP4 inhibitor
ab145144 · 1 mg
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Catalog No: ab145144
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 294.4 Da, Purity >99 %. Highly selective multidrug resistance protein 4 MRP4 inhibitor IC50 = 1.5 muM . Blocked transport of MRP4 substrates 6-Mercaptopurine, SN 38, cAMP, D-Luciferin and E217betaG. No detectable effect on MRP4 homologs MRP1, 2, 3 or 5, and related transporters P-gp and ABCG2 in vitro. Low cellular toxicity, and high microsomal and acid stability. Chemically distinctive to Ceefourin 2 ab145145 .
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