CD80 Rabbit Polyclonal Antibody

Description

EnkiLife offers the CD80 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: T-lymphocyte activation antigen CD80 (Activation B7-1 antigen;BB1;CTLA-4 counter-receptor B7.1;B7;CD antigen CD80). The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 Background: The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells., Research Area: Cell adhesion molecules (CAMs);Toll_Like;Intestinal immune network for IgA production;Type I diabetes mellitus;Autoimmune thyroid disease;Systemic lupus erythematosus;Allograft rejection;Graft-versus-host disease;Viral myocarditis;