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Cabazitaxel
ab287035 · 5 mg
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Catalog No: ab287035
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 835.9 Da, Purity >98 %. Cabazitaxel ab287035 is a second generation semisynthetic taxane derived from 10-deacetylbaccatin with potent anticancer activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Cabazitaxel is more potent than docetaxel in P-glycoprotein-expressing cell lines with in vitro acquired resistance to taxanes or other chemotherapeutic agents.
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