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BRAFV600E/JNK-IN-1
GENERAL CATALOGUE

BRAFV600E/JNK-IN-1

HY-173153 · 50 mg

MedChemExpress · Cat: HY-173153

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Catalog No: HY-173153
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

BRAFV600E/JNK-IN-1 Compound 14c is an inhibitor of JNK1, JNK2, JNK3 and BRAFV600E, with IC50 values of 0.51 ?M, 0.53 ?M, 1.02 ?M and 0.009 ?M, respectively. BRAFV600E/JNK-IN-1 can inhibit the phosphorylation of MEK1/2 and ERK1/2. In addition, BRAFV600E/JNK-IN-1 can inhibit tumor cell proliferation, NO release and PGE2 production, and has anti-tumor and anti-inflammatory activities.

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