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Bisindolylmaleimide II, PKC inhibitor
ab144206 · 1 mg
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Catalog No: ab144206
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 438.5 Da, Purity >97 %. Potent, selective ATP-competitive PKC inhibitor IC50 values are 0.01, 0.75 and 2 muM for PKC, phosphorylase kinase and PKA respectively . Potent noncompetitive nAChR antagonist IC50 = 0.03 muM, catecholamine secretion in nicotine-stimulated PC-12 cells . Shows more potent antinicotinic effects than Bisindolylmaleimide IV ab144208 and V ab144205 . Induces apoptosis and shows antiproliferative effects.
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