

HY-B0557 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B0557
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medchemexpress.com/Bisacodyl.htmlDescription
Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect.