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AZD-3965
ab286958 · 1 mg
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Catalog No: ab286958
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 515.5 Da, Purity >98 %. A potent and selective monocarboxylate transporter 1 MCT1 inhibitor with a binding affinity of 1.6 nM; it is 6-fold selective over MCT2 and does not inhibit MCT4 even at 10 muM. AZD 3965 increases intratumor lactate levels and decreases tumor growth in mice bearing COR-L103 small cell lung cancer SCLC xenografts.
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