GENERAL CATALOGUE
ATX968
HY-156784 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-156784
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medchemexpress.com/dhx9-in-2.htmlCatalog No: HY-156784
CAS No: 2973395-71-8
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ATX968 example 31 is an orally active, potent and selective inhibitor of ATP-dependent RNA helicase A DHX9 , with the EC50 of 0.054 ?M in circBRIP1. ATX968 results in robust and durable tumor growth inhibition or regression in mouse xenograft studies with MSI-H/dMMR colorectal cancer cell lines.
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