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Apoptozole
ab287038 · 5 mg
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Catalog No: ab287038
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 625.6 Da, Purity >98 %. Apoptozole is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14 muM, respectively. Apoptozole dose-dependently induces apoptosis in cancer cells IC50 = 5-7 muM . It prevents the association of Hsp70 with apoptotic protease-activating factor 1 and triggers caspase activation in HeLa cells.
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