Anti-PON3 Antibody

Description

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein HDL . The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein LDL , a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. provided by RefSeq, Jul 2008