ANG Stable Knockout U2OS Cell Line (U2OS ANG KO5)

Description

The ANG Stable Knockout U2OS Cell Line U2OS ANG KO5 was developed using CRISPR-Cas9 technology to completely knock out the angiogenin ANG gene in U2OS cells, a human osteosarcoma cell line. Angiogenin is a ribonuclease involved in angiogenesis and cellular response to stress, particularly in the context of tumor growth and metastasis. The knockout of ANG in U2OS cells provides a valuable model for studying the role of angiogenin in cancer biology, including its involvement in tumorigenesis, cell migration, and angiogenesis. This cell line is particularly useful for exploring potential therapeutic strategies targeting angiogenin in cancer treatment.