

HY-P9977A · 1 mg
MedChemExpress · Cat: HY-P9977A
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medchemexpress.com/amivantamab-fut8-ko.htmlDescription
Amivantamab FUT8-KO is an anti-EGFR-MET monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene FUT8 knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Amivantamab FUT8-KO inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells.







